Netter's essential biochemistry /

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Hlavní autor: Ronner, Peter, 1951- (Autor)
Další autoři: Netter, Frank H. 1906-1991 (Ilustrátor)
Typ dokumentu: Kniha
Jazyk:Angličtina
Vydáno: Philadelphia, PA: Elsevier, [2018]
Témata:
On-line přístup:Elektronická verze přístupná pouze pro studenty a pracovníky MU
Příbuzné jednotky:Tištěná verze:: Netter's essential biochemistry.
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100 1 |a Ronner, Peter,  |d 1951-  |4 aut 
245 1 0 |a Netter's essential biochemistry /  |c Peter Ronner ; illustrations by Frank H. Netter 
264 1 |a Philadelphia, PA:  |b Elsevier,  |c [2018] 
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300 |a 1 online zdroj (xii, 482 stran) :  |b ilustrace 
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505 0 |a Front Cover; Inside Front Cover; Marketing page; Netter's Essential Biochemistry; Copyright Page; Dedication; About the Author; Acknowledgments; Coauthors and Chapter Reviewers; About the Artist; Frank H. Netter, MD; Preface; Table Of Contents; 1 Human Karyotype and the Structure of DNA; Learning Objectives; Synopsis; 1. Chemical Structure of DNA; 2. Hydrogen Bonding Between Complementary Bases; 3. DNA Double Helix; 4. Packing of DNA Double Helices Into Chromatids; 5. Changes in DNA Topology; 6. Human Karyotype; Summary; Further Reading; Review Questions; 2 DNA Repair and Therapy of Cancer. 
505 8 |a Learning ObjectivesSynopsis; 1. Base-Excision Repair; 2. Mismatch Repair; 3. Nucleotide-Excision Repair; 4. Repair of Double-Strand Breaks and Interstrand Crosslinks; 4.1. Nonhomologous End Joining; 4.2. Homologous Recombination Repair (Homology-Directed Repair); 5. DNA Damage Response Halts the Cell Cycle and Regulates Apoptosis; Summary; Further Reading; Review Questions; 3 DNA Replication; Learning Objectives; Synopsis; 1. DNA Replication; 2. Translesion Dna Synthesis; 3. Replication of the Ends of Chromosomes (Telomeres); Summary; Further Reading; Review Questions. 
505 8 |a 4 Clinical Tests Based on DNA or RNALearning Objectives; Synopsis; 1. Conventional Cytogenetics and Fluorescence in Situ Hybridization; 2. DNA Amplification by Polymerase Chain Reaction; 3. Electrophoresis and Melting Curve Analysis of DNA; 4. DNA Microarray-Based Technologies; 5. DNA Sequencing; 5.1. Sanger Sequencing; 5.2. Massive Parallel Sequencing; 6. Selected Clinical Applications of DNA-Based Testing; 6.1. Prenatal Diagnosis; 6.2. Other Common Nucleic Acid-Based Tests; Summary; Further Reading; Review Questions; 5 Basic Genetics for Biochemistry; Learning Objectives; Synopsis. 
505 8 |a 1. Chromosomes and Alleles2. Imprinting and Patterns of Inheritance; 3. Mutations and Markers; Summary; Review Question; 6 Transcription and RNA Processing; Learning Objectives; Synopsis; 1. DNA Methylation and Packing Impede Transcription; 2. The Process of Transcription; 3. Processing of RNA During and After Transcription; 3.1. Capping of Pre-mRNA; 3.2. Polyadenylation of Pre-mRNA; 3.3. Splicing of Pre-mRNA; 3.4. Alternative Splicing of Pre-mRNA; 3.5. Export of mRNA Into the Cytosol; 3.6. Degradation of mRNA; Summary; Further Reading; Review Questions. 
505 8 |a 7 Translation and Posttranslational Protein ProcessingLearning Objectives; Synopsis; 1. Codons and the Genetic Code; 2. Transfer RNAs; 3. Ribosomes Translate mRNA Into Protein; 4. Posttranslational Modification; 4.1. General Comments; 4.2. Glycosylation; 4.3. Acylation With Fatty Acids and Prenylation; 4.4. Phosphorylation, Sulfation, and Nitrosylation; 4.5. Ubiquitylation and SUMOylation; 5. Protein Sorting and Quality Control; Summary; Further Reading; Review Questions; 8 Cell Cycle and Cancer; Learning Objectives; Synopsis; 1. Cell Cycle and Its Regulation. 
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