Cushing's disease : an often misdiagnosed and not so rare disorder /
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| Další autoři: | , |
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| Typ dokumentu: | Kniha |
| Jazyk: | Angličtina |
| Vydáno: |
London :
Academic Press,
2017
|
| Témata: | |
| On-line přístup: | Elektronická verze přístupná pouze pro studenty a pracovníky MU |
| Příbuzné jednotky: | Tištěná verze::
Cushing's disease : an often misdiagnosed and not so rare disorder. |
Obsah:
- Cover ; Title page; Copyright page; Dedication; Contents; List of Contributors; Preface; List of Abbreviations; Introductiona; Chapter 1
- The Pituitary Gland: Anatomy, Physiology, and its Function as the Master Gland; 1
- Introduction; 2
- History; 3
- Embryology; 4
- Anatomy; 4.1
- Histology; 4.2
- Hypothalamus; 4.3
- Vascular Anatomy; 4.4
- Surgical Anatomy; 4.4.1
- Nasal Cavity Anatomy; 4.4.2
- Sphenoid Sinus Anatomy; 4.5
- Radiographic Anatomy; 5
- Physiology; 5.1
- Hypothalamic Physiology; 5.1.1
- Hypothalamus-Pituitary-Adrenal Axis; 5.1.2
- Hypothalamus-Pituitary-Thyroid Axis.
- 5.1.3
- Hypothalamus-Pituitary-Growth Hormone Axis; 5.1.4
- Hypothalamus-Pituitary-Gonadal Axis; 5.1.4.1
- Effects on Men; 5.1.4.2
- Effects on Women; 5.1.5
- Lactotroph Axis; 5.2
- Posterior Pituitary Function; 5.3
- Intermediate Gland Function; 6
- Homeostasis; 7
- Hypopituitarism; 8
- Conclusions; References; Chapter 2
- Epidemiology and Etiology of Cushing's Disease; 1
- Introduction; 2
- Epidemiology of Cushing's Disease; 2.1
- Incidence and Prevalence; 2.1.1
- Population-Based Data; 2.1.2
- Hypercortisolism in Patients with Incidentally Found Pituitary Masses.
- 2.1.3
- "Occult" Cushing's Disease in Patients with Diabetes Mellitus, Hypertension, Polycystic Ovary Syndrome, Obesity, an ... 2.2
- Mortality; 2.3
- Long-Term Morbidity and Quality of Life; 3
- Etiology of Cushing's Disease; 3.1
- Mutations in the Deubiquitinase Gene (USP8); 3.2
- Multiple Endocrine Neoplasia 1 Syndrome; 3.3
- Mutations in the Aryl-hydrocarbon Receptor Interacting Protein (AIP) Gene; 3.4
- Other Gene Mutations; 3.4.1
- Mutations in the DICER1 (Ribonuclease Type III) Gene; 3.4.2
- Mutations in Cyclin-Dependent Kinase Inhibitor Subtype 1B Gene; 3.4.3
- Mutations in the GR Gene.
- 3.4.4
- Mutations in the p53 Gene; 3.5
- Gene and Protein Expression Abnormalities in Corticotropinomas; 4
- Conclusions; Disclosures; References; Chapter 3
- Physical Presentation of Cushing's Syndrome: Typical and Atypical Presentations; 1
- Introduction; 2
- Symptoms of Cushing's disease; 2.1
- Subjective Symptoms; 2.2
- Objective Symptoms; 2.3
- Atypical Symptoms; 3
- Signs of Cushing's disease; 4
- Comorbidities associated with Cushing's syndrome; 4.1
- Diabetes Mellitus; 4.2
- Hypertension; 4.3
- Sleep Disturbances; 4.4
- Osteoporosis and Bone Fractures; 4.5
- Depression and Psychosis.
- 4.6
- Memory and Cognitive Function; 5
- Cyclical Cushing's syndrome; 6
- Cushing's syndrome in athletes; 7
- Pseudo-Cushing's disease; 8
- Cushing's syndrome in children and adolescents; 9
- Conclusions; Chapter 4
- The Cognitive, Psychological, and Emotional Presentation of Cushing's Disease; 1
- Introduction; 2
- Cognitive and emotional aspects of Cushing's disease; 2.1
- Clinical Presentations; 2.1.1
- Effects on Psychological Health; 2.1.2
- Effects on Sleep; 2.1.3
- Effects on Cognitive Function; 3
- Effects of glucocorticoid excess on brain structures; 3.1
- Hippocampal Size and Atrophy.
- 3.1.1
- Animal Models.