Cushing's disease : an often misdiagnosed and not so rare disorder /

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Další autoři: Laws, Edward R., Jr. (Editor), Pace, Louise (Autor úvodu atd.)
Typ dokumentu: Kniha
Jazyk:Angličtina
Vydáno: London : Academic Press, 2017
Témata:
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245 0 0 |a Cushing's disease :  |b an often misdiagnosed and not so rare disorder /  |c edited by Edward R. Laws, Jr. ; with an introduction by Louise Pace 
264 1 |a London :  |b Academic Press,  |c 2017 
264 4 |c ©2017 
300 |a 1 online zdroj (xxi, 216 stran) :  |b ilustrace 
336 |a text  |b txt  |2 rdacontent 
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505 0 |a Cover ; Title page; Copyright page; Dedication; Contents; List of Contributors; Preface; List of Abbreviations; Introductiona; Chapter 1 -- The Pituitary Gland: Anatomy, Physiology, and its Function as the Master Gland; 1 -- Introduction; 2 -- History; 3 -- Embryology; 4 -- Anatomy; 4.1 -- Histology; 4.2 -- Hypothalamus; 4.3 -- Vascular Anatomy; 4.4 -- Surgical Anatomy; 4.4.1 -- Nasal Cavity Anatomy; 4.4.2 -- Sphenoid Sinus Anatomy; 4.5 -- Radiographic Anatomy; 5 -- Physiology; 5.1 -- Hypothalamic Physiology; 5.1.1 -- Hypothalamus-Pituitary-Adrenal Axis; 5.1.2 -- Hypothalamus-Pituitary-Thyroid Axis. 
505 8 |a 5.1.3 -- Hypothalamus-Pituitary-Growth Hormone Axis; 5.1.4 -- Hypothalamus-Pituitary-Gonadal Axis; 5.1.4.1 -- Effects on Men; 5.1.4.2 -- Effects on Women; 5.1.5 -- Lactotroph Axis; 5.2 -- Posterior Pituitary Function; 5.3 -- Intermediate Gland Function; 6 -- Homeostasis; 7 -- Hypopituitarism; 8 -- Conclusions; References; Chapter 2 -- Epidemiology and Etiology of Cushing's Disease; 1 -- Introduction; 2 -- Epidemiology of Cushing's Disease; 2.1 -- Incidence and Prevalence; 2.1.1 -- Population-Based Data; 2.1.2 -- Hypercortisolism in Patients with Incidentally Found Pituitary Masses. 
505 8 |a 2.1.3 -- "Occult" Cushing's Disease in Patients with Diabetes Mellitus, Hypertension, Polycystic Ovary Syndrome, Obesity, an ... 2.2 -- Mortality; 2.3 -- Long-Term Morbidity and Quality of Life; 3 -- Etiology of Cushing's Disease; 3.1 -- Mutations in the Deubiquitinase Gene (USP8); 3.2 -- Multiple Endocrine Neoplasia 1 Syndrome; 3.3 -- Mutations in the Aryl-hydrocarbon Receptor Interacting Protein (AIP) Gene; 3.4 -- Other Gene Mutations; 3.4.1 -- Mutations in the DICER1 (Ribonuclease Type III) Gene; 3.4.2 -- Mutations in Cyclin-Dependent Kinase Inhibitor Subtype 1B Gene; 3.4.3 -- Mutations in the GR Gene. 
505 8 |a 3.4.4 -- Mutations in the p53 Gene; 3.5 -- Gene and Protein Expression Abnormalities in Corticotropinomas; 4 -- Conclusions; Disclosures; References; Chapter 3 -- Physical Presentation of Cushing's Syndrome: Typical and Atypical Presentations; 1 -- Introduction; 2 -- Symptoms of Cushing's disease; 2.1 -- Subjective Symptoms; 2.2 -- Objective Symptoms; 2.3 -- Atypical Symptoms; 3 -- Signs of Cushing's disease; 4 -- Comorbidities associated with Cushing's syndrome; 4.1 -- Diabetes Mellitus; 4.2 -- Hypertension; 4.3 -- Sleep Disturbances; 4.4 -- Osteoporosis and Bone Fractures; 4.5 -- Depression and Psychosis. 
505 8 |a 4.6 -- Memory and Cognitive Function; 5 -- Cyclical Cushing's syndrome; 6 -- Cushing's syndrome in athletes; 7 -- Pseudo-Cushing's disease; 8 -- Cushing's syndrome in children and adolescents; 9 -- Conclusions; Chapter 4 -- The Cognitive, Psychological, and Emotional Presentation of Cushing's Disease; 1 -- Introduction; 2 -- Cognitive and emotional aspects of Cushing's disease; 2.1 -- Clinical Presentations; 2.1.1 -- Effects on Psychological Health; 2.1.2 -- Effects on Sleep; 2.1.3 -- Effects on Cognitive Function; 3 -- Effects of glucocorticoid excess on brain structures; 3.1 -- Hippocampal Size and Atrophy. 
505 8 |a 3.1.1 -- Animal Models. 
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