Genetická variabilita u nemocných s kolorektálním karcinomem
Kolorektalni karcinom je onemocneni s vysokou incidenci, jez radi Ceskou Republiku na predni mista ve svete. Predkladana prace analyzuje u souboru 100 pacientu dobu preziti podle typu provedeného operacniho vykonu (Milesova operace, nizka resekce), jejich pooperacni stav ve vztahu k typu operacniho...
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| Format: | Thesis Manuscript |
| Language: | Czech |
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2012
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| Online Access: | http://is.muni.cz/th/21804/lf_d/ |
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| 072 | 7 | |a 616 |x Patologie. Klinická medicína |2 Konspekt |9 14 | |
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| 100 | 1 | |a Veselý, Martin |% UČO 21804 |* [absolvent LF MU] |4 dis | |
| 242 | 1 | 0 | |a Genetic variability in patients with colorectal carcinoma |y eng |
| 245 | 1 | 0 | |a Genetická variabilita u nemocných s kolorektálním karcinomem |h [rukopis] / |c Martin Veselý |
| 260 | |c 2012 | ||
| 300 | |a 75 l. | ||
| 500 | |a Vedoucí práce: Petr Vlček | ||
| 502 | |a Dizertace (Ph.D.)--Masarykova univerzita, Lékařská fakulta, 2012 | ||
| 520 | 2 | |a Kolorektalni karcinom je onemocneni s vysokou incidenci, jez radi Ceskou Republiku na predni mista ve svete. Predkladana prace analyzuje u souboru 100 pacientu dobu preziti podle typu provedeného operacniho vykonu (Milesova operace, nizka resekce), jejich pooperacni stav ve vztahu k typu operacniho vykonu z hlediska fyzického a psychického. Dale se zabyva analyzou genu zanetlivych cytokinu (angiotensinogen, interleukin 6, gen pro leptinovy receptor) jako potencionalnich faktoru ovlivnujich incidenci a vlastni rust nadoru a celkovou progresi onemocneni. Zaroven tyto genotypové rozdily analyzuje z hlediska typu provedeného operacniho vykonu. |% cze | |
| 520 | 2 | 9 | |a The colorectal karcinoma is a disease with high incidence, that brings the Czech Republic to front positions in the world. The presented dissertation analyses the survival time of 100 patients according to the type of operation (amputation recti, low anterior resection), their postoperative condition accordinrg to thein physical and mental state. Moreover it analyses the genes of inflammatory cytokines /angiotensinogen, interleukin6, leptin-receptor gene)as potentional factors that influate the incidence and tumor growth and the total progression of the disease. The genotypic differences are also analyzed according to the type of surgery. |9 eng |
| 650 | 0 | 7 | |a angiotensinogen |2 czmesh |
| 650 | 0 | 7 | |a kolorektální nádory |x genetika |2 czmesh |
| 650 | 0 | 7 | |a lékařská genetika |2 czmesh |
| 650 | 0 | 2 | |a Angiotensinogen |
| 650 | 0 | 2 | |a Colorectal Neoplasms |
| 650 | 0 | 2 | |a Genetics, Human |
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| 700 | 1 | |a Vlček, Petr |7 xx0031919 |% UČO 2251 |4 ths | |
| 710 | 2 | |a Masarykova univerzita. |b Chirurgická klinika, I. |7 xx0037880 |4 dgg | |
| 856 | 4 | 1 | |u http://is.muni.cz/th/21804/lf_d/ |
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