Interakce alkaloidu berberinu s d(AAGAATTCTT)2
Nekovalentné interakcie planárnych aromatických systémov s nukleovými kyselinami sú v súčasnosti vďaka svojmu významu predmetom intenzívneho štúdia. Cieľom práce bolo získať a spracovať poznatky o spôsobe väzby týchto systémov na DNA s dôrazom na kvartérne protoberberínové alkaloidy. V experimentáln...
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| Typ dokumentu: | VŠ práce nebo rukopis |
| Jazyk: | Slovenština |
| Vydáno: |
2007.
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| Témata: | |
| On-line přístup: | http://is.muni.cz/th/151360/prif_b/ |
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| 072 | 7 | |a 577 |x Biochemie. Molekulární biologie. Biofyzika |2 Konspekt |9 2 | |
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| 100 | 1 | |a Babinský, Martin |% UČO 151360 |* [absolvent PřírF MU] |4 dis | |
| 242 | 1 | 0 | |a Interaction of berberine alkaloid with d(AAGAATTCTT)2 |y eng |
| 245 | 1 | 0 | |a Interakce alkaloidu berberinu s d(AAGAATTCTT)2 |h [rukopis] / |c Martin Babinský |
| 260 | |c 2007. | ||
| 300 | |a 41 l. | ||
| 500 | |a Vedoucí práce: Radek Marek. | ||
| 502 | |a Bakalářská práce (Bc.)--Masarykova univerzita, Přírodovědecká fakulta, 2007. | ||
| 520 | 2 | |a Nekovalentné interakcie planárnych aromatických systémov s nukleovými kyselinami sú v súčasnosti vďaka svojmu významu predmetom intenzívneho štúdia. Cieľom práce bolo získať a spracovať poznatky o spôsobe väzby týchto systémov na DNA s dôrazom na kvartérne protoberberínové alkaloidy. V experimentálnej časti sa pomocou NMR spektroskopie a molekulového modelovania určovala štruktúra komplexu alkaloidu berberínu a oligonukleotidu so sekvenciou d(AAGAATTCTT)2. |% cze | |
| 520 | 2 | 9 | |a Noncovalent interactions of palanar systems and nucleic acids are being intensively studied due to their great importance. The aim of this thesis was to retrieve information about the mode of interaction between planar aromatic systems and DNA with the emphasis put on quaternary protoberberine alkaloids. The structure of complex between berberine and oligonucleotide of sequence d(AAGAATTCTT)2 has been studied experimentally using NMR spectroscopy and methods of molecular modelling. |9 eng |
| 650 | 0 | 7 | |a berberinové alkaloidy |2 czmesh |
| 650 | 0 | 7 | |a DNA (nukleová kyselina) |7 ph116977 |2 czenas |
| 650 | 0 | 7 | |a nukleové kyseliny |7 ph115470 |2 czenas |
| 650 | 0 | 7 | |a oligonukleotidy |2 czmesh |
| 650 | 0 | 9 | |a deoxyribonucleic acid |2 eczenas |
| 650 | 0 | 9 | |a nucleic acids |2 eczenas |
| 655 | 7 | |a bakalářské práce |7 fd132403 |2 czenas | |
| 655 | 9 | |a bachelor's theses |2 eczenas | |
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| 700 | 1 | |a Marek, Radek, |d 1967- |7 xx0098494 |% UČO 381 |4 ths | |
| 710 | 2 | |a Masarykova univerzita. |b Ústav biochemie |7 ko2015866760 |4 dgg | |
| 856 | 4 | 1 | |u http://is.muni.cz/th/151360/prif_b/ |
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