Introduction to drug disposition and pharmacokinetics /
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Hlavní autoři: | , |
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Typ dokumentu: | Kniha |
Jazyk: | Angličtina |
Vydáno: |
Chichester :
Wiley,
2017
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Vydání: | First published |
Témata: | |
On-line přístup: | Elektronická verze přístupná pouze pro studenty a pracovníky MU |
Příbuzné jednotky: | Tištěná verze::
Introduction to drug disposition and pharmacokinetics. |
Obsah:
- Drug Administration and Distribution
- Drug Metabolism and Excretion
- Single-compartment Pharmacokinetic Models
- Multiple-compartment and Non-compartment Pharmacokinetic Models
- Kinetics of Metabolism and Excretion
- Clearance, Protein Binding and Physiological Modelling
- Quantitative Pharmacological Relationships
- Pharmacokinetics of Large Molecules
- Pharmacogenetics and Pharmacogenomics
- Additional Factors Affecting Plasma Concentrations
- Effects of Age and Disease on Drug Disposition
- Drug Interactions and Toxicity
- Perspectives and Prospects
- Appendix 1: Mathematical Concepts and the Trapezoidal Method
- Appendix 2: Dye Models to Teach Pharmacokinetics
- Appendix 3: Curve Fitting
- Appendix 4: Pharmacokinetic Simulations.