Chronic obstructive pulmonary disease : a systemic inflammatory disease /

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Bibliographic Details
Other Authors: Nakamura, Hiroyuki (Editor), Aoshiba, Kazutetsu (Editor)
Format: Book
Language:English
Published: Singapore : Springer, [2017]
Series:Respiratory disease series,
Subjects:
Online Access:Elektronická verze přístupná pouze pro studenty a pracovníky MU
Related Items:Tištěná verze:: Chronic obstructive pulmonary disease : a systemic inflammatory disease.
Table of Contents:
  • Preface; References; Contents; Part I: Definition and Epidemiology; Chapter 1: Definition of Chronic Obstructive Pulmonary Disease (COPD): Is the Latest GOLD Classification of Severity Still Val ... ; 1.1 Introduction; 1.2 Historical Transition of the Concept of COPD; 1.3 Difference Between COPD and Bronchial Asthma; 1.4 Chronic Bronchitis and Pulmonary Emphysema; 1.5 Global Initiative for Chronic Obstructive Lung Disease (GOLD); 1.6 Combined COPD Assessment; 1.7 Conclusion; References; Chapter 2: Epidemiology of COPD: Why Is the Disease So Poorly Recognized?; 2.1 Introduction.
  • 2.2 Risk Factors of COPD2.2.1 Cigarette Smoking; 2.2.2 Other Risk Factors; 2.2.2.1 Genetic Factors; 2.2.2.2 Environmental Factors; Occupational Airborne Particles; Air Pollution; Indoor Air Pollutants; Outdoor Air Pollution; 2.2.2.3 Low Socioeconomic Status; 2.3 Decline in FEV1 in Patients with COPD; 2.4 Incidence of COPD; 2.5 Prevalence of COPD; 2.6 Undiagnosed COPD; 2.7 Impact of COPD on Health Status in the General Population; 2.8 Conclusions; References; Part II: Genetic Predisposition and Pathogenic Mechanisms.
  • Chapter 3: Genetic Predisposition to COPD: Are There Any Relevant Genes Determining the Susceptibility to Smoking?3.1 Introduction; 3.2 Investigation of the Genes Related to COPD Pathogenesis: The Era Before GWAS; 3.3 Genome-Wide Association Studies (GWASs) for Susceptibility Genes of COPD; 3.4 Recent Progress of Studies of COPD Genetics in GWAS Era (I): Relevant Genes Determining the Susceptibility to Smoking; 3.5 Recent Progress of Studies of COPD Genetics in GWAS Era (II): Gene Related to Critical Subtypes or Phenotypes of COPD.
  • 3.6 Recent Progress of Studies of COPD Genetics in GWAS Era (III): Novel Strategy for Research on COPD Genetics with Multi-omi ... 3.7 Recent Progress of Studies of COPD Genetics in GWAS Era (IV): Next-Generation Sequencing and Arrays; 3.8 Recent Progress of Studies of COPD Genetics in GWAS Era (V): Pharmacogenetics and Pharmacogenomics in COPD; 3.9 Conclusions; References; Chapter 4: Pathogenesis of COPD (Persistence of Airway Inflammation): Why Does Airway Inflammation Persist After Cessation of ... ; 4.1 Introduction; 4.2 Airway Inflammation and Changes in COPD.
  • 4.2.1 Airway Structure and Mucus Production in Patients with COPD4.2.2 Lung Destruction in COPD; 4.2.3 Inflammatory Cells and Cytokines in the Airway in COPD; 4.3 Airway Inflammation After Smoking Cessation; 4.3.1 Innate Immune System; 4.3.1.1 The Role of TLRs; 4.3.1.2 The Role of NLRs; 4.3.1.3 The Role of RLRs; 4.3.1.4 The Role of RAGE; 4.3.2 Adaptive Immune System; 4.3.2.1 The Role of B Cells; 4.3.2.2 The Role of T Cells; 4.3.3 COPD Deterioration After Smoking Cessation; 4.3.3.1 COPD Deterioration by COPD Itself; 4.3.3.2 COPD Deterioration by Latent Respiratory Infection.