Pharmacokinetics and toxicokinetics /
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| Hlavní autor: | |
|---|---|
| Typ dokumentu: | Kniha |
| Jazyk: | Angličtina |
| Vydáno: |
Boca Raton, FL :
CRC Press,
[2015]
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| Témata: | |
| On-line přístup: | Elektronická verze přístupná pouze pro studenty a pracovníky MU |
| Příbuzné jednotky: | Tištěná verze::
Pharmacokinetics and toxicokinetics. |
Obsah:
- Chapter 1. The influence of routes of administration on ADME
- chapter 2. Mechanisms of absorption and permeation of xenobiotics
- chapter 3. In Vivo distribution of xenobiotics
- chapter 4. Elimination rate, clearance, and the theoretical models
- chapter 5. Renal excretion of xenobiotics and estimation of related PK/TK parameters and constants
- chapter 6. Biotransformation of xenobiotics
- chapter 7. Kinetics of In Vitro metabolism : assimilation of intrinsic clearance in hepatic clearance
- chapter 8. Pharmaceutical, biopharmaceutical, and physiological factors influencing oral absorption : mechanistic absorption models
- chapter 9. Mathematical modeling in pharmacokinetics and toxicokinetics
- chapter 10. PK/TK analysis of instantaneous exposure to xenobiotics (single bolus injection)
- chapter 11. PK/TK analysis of continuous zero-order exposure to xenobiotics (intravenous infusion)
- chapter 12. PK/TK analysis of xenobiotics absorbed via an extravascular route of administration (oral administration)
- chapter 13. PK/TK of xenobiotics absorbed through the skin (transdermal absorption)
- chapter 14. PK/TK analysis of multiple dosing
- chapter 15. Bioavailability, bioequivalence, and biosimilar evaluations
- chapter 16. Preclinical PK/TK and clinical trials
- chapter 17. Population pharmacokinetics/toxicokinetics
- chapter 18. Quantitative extrapolation interspecies scaling/low dose extrapolation