The AH receptor in biology and toxicology /

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Další autoři: Pohjanvirta, Raimo (Editor)
Typ dokumentu: Kniha
Jazyk:Angličtina
Vydáno: Hoboken, New Jersey : Wiley, [2012]
Témata:
On-line přístup:Elektronická verze přístupná pouze pro studenty a pracovníky MU
Příbuzné jednotky:Tištěná verze:: AH receptor in biology and toxicology.
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072 7 |a 615  |x Farmacie. Farmakologie  |2 Konspekt  |9 14 
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245 0 4 |a The AH receptor in biology and toxicology /  |c edited by Raimo Pohjanvirta 
264 1 |a Hoboken, New Jersey :  |b Wiley,  |c [2012] 
264 4 |c ©2012 
300 |a 1 online zdroj (xiii, 533 stran) :  |b ilustrace 
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505 0 |a Frontmatter -- Color Plates -- Historical Background. History of Research on the AHR / Thomas A Gasiewicz, Ellen C Henry -- AHR as a Ligand-Activated Transcription Factor. Overview of AHR Functional Domains and the Classical AHR Signaling Pathway: Induction of Drug Metabolizing Enzymes / Qiang Ma -- Role of Chaperone Proteins in AHR Function / Iain A Murray, Gary H Perdew -- AHR Ligands: Promiscuity in Binding and Diversity in Response / Danica DeGroot, Guochun He, Domenico Fraccalvieri, Laura Bonati, Allesandro Pandini, Michael S Denison -- Dioxin Response Elements and Regulation of Gene Transcription / Hollie Swanson -- The AHR/ARNT Dimer and Transcriptional Coactivators / Oliver Hankinson -- Regulation of AHR Activity by the AHR Repressor (AHRR) / Yoshiaki Fujii-Kuriyama, Kaname Kawajiri -- Influence of HIF1a and NRF2 Signaling on AHR-Mediated Gene Expression, Toxicity, and Biological Functions / Thomas Haarmann-Stemmann, Josef Abel ---Functional Interactions of AHR with other Receptors / Sara Brunnberg, Elin Swedenborg, Jan-Ake Gustafsson -- The E3 Ubiquitin Ligase Activity of Transcription Factor AHR Permits Nongenomic Regulation of Biological Pathways / Fumiaki Ohtake, Shigeaki Kato -- Epigenetic Mechanisms in AHR Function / Chia-I Ko, Alvaro Puga -- AHR as a Mediator of Xenobiotic Toxicities: Dioxins as a Key Example. Role of the AHR and its Structure in TCDD Toxicity / Raimo Pohjanvirta, Merja Korkalainen, Ivy D Moffat, Paul C Boutros, Allan B Okey -- Nongenomic Route of Action of TCDD: Identity, Characteristics, and Toxicological Significance / Fumio Matsumura -- Interspecies Heterogeneity in the Hepatic Transcriptomic Response to AHR Activation by Dioxin / Paul C Boutros -- Dioxin-Activated AHR: Toxic Responses and the Induction of Oxidative Stress / Sidney J Stohs, Ezdihar A Hassoun -- Dioxin Activated AHR and Cancer in Laboratory Animals / Dieter Schrenk, Martin Chopra ---Teratogenic Impact of Dioxin Activated AHR in Laboratory Animals / Barbara D Abbott -- The Developmental Toxicity of Dioxin to the Developing Male Reproductive System in the Rat: Relevance of the AHR for Risk Assessment / David R Bell -- TCDD, AHR, and Immune Regulation / Nancy I Kerkvliet -- Effects of Dioxins on Teeth and Bone: The Role of AHR / Matti Viluksela, Hanna M Miettinen, Merja Korkalainen -- Impacts of Dioxin-Activated AHR Signaling in Fish and Birds / Michael T Simonich, Robert L Tanguay -- Adverse Health Outcomes Caused By Dioxin-Activated AHR in Humans / Sally S White, Suzanne E Fenton, Linda S Birnbaum -- The Toxic Equivalency Principle and its Application in Dioxin Risk Assessment / Jouko Tuomisto -- AHR-Active Compounds in the Human Diet / Stephen Safe, Gayathri Chadalapaka, Indira Jutooru -- Modulation of AHR Function by Heavy Metals and Disease States / Anwar Anwar-Mohammed, Ayman O S El-Kadi ---Transgenic Mice with a Constitutively Active AHR: A Model for Human Exposure to Dioxin and other AHR Ligands / Patrik Andersson, Sara Brunnberg, Carolina Wejheden, Lorenz Poellinger, Annika Hanberg -- AHR as a Physiological Regulator. Structural and Functional Diversification of AHRs during Metazoan Evolution / Mark E Hahn, Sibel I Karchner -- Invertebrate AHR Homologs: Ancestral Functions in Sensory Systems / Jo Anne Powell-Coffman, Hongtao Qin -- Role of AHR in the Development of the Liver and Blood Vessels / Sahoko Ichihara -- Involvement of the AHR in Cardiac Function and Regulation of Blood Pressure / Jason A Scott, Mary K Walker -- Involvement of the AHR in Development and Functioning of the Female and Male Reproductive Systems / Bethany N Karman, Isabel Herǹndez-Ochoa, Ayelet Ziv-Gal, Jodi A Flaws -- The AHR in the Control of Cell Cycle and Apoptosis / Cornelia Dietrich ---The AHR Regulates Cell Adhesion and Migration by Interacting with Oncogene and Growth Factor-Dependent Signaling / Angel Carlos Roman, Jose M Carvajal-Gonzalez, Sonia Mulero-Navarro, Aurea Gomez-Duran, Eva M Rico-Leo, Jaime M Merino, Pedro M Fernandez-Salguero -- The Physiological Role of AHR in the Mouse Immune System / Charlotte Esser -- AHR and the Circadian Clock / Shelley A Tischkau -- Index. 
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