Cancer gene therapy : past achievements and future challenges - Habib, Nagy A. (New York : Kluwer Academic Publishers, 2000)
The Clinical Problem -- Management Problems in Oncology -- Vectors -- Adenoviral Vectors -- Retrovirus Vectors -- Targetable Gene Delivery Vectors -- Human ?-fetoprotein Transcriptional Regulatory Sequences -- Tumor-Targeted Salmonella -- Mutant Adenoviruses Selectively Replication-Competent in Tumor Cells -- Polyoma and Papilloma Virus Vectors For Cancer Gene Therapy -- Cochleates -- The Use Of Skeletal Muscle To Express Genes For The Treatment Of Cancer -- Cell Cycle Control -- Adhesion Molecules in Cancer Biology -- Cell Cycle Control -- Apoptosis -- Killer/DR5, A Novel DNA-Damage Inducible Death Receptor Gene, Links the p53-Tumor Suppressor to Caspase Activation and Apoptotic Death -- Apoptin® -- Adenovirus-Mediated Herpes Simplex Thymidine Kinase Gene Therapy For Brain Tumors -- Development of Clinical Trial of E1A Gene Therapy Targeting HER-2/neu-overexpressing Breast and Ovarian Cancer -- Tumout Suppressor Genes -- Pre-clinical Studies with Tumor Suppressor Genes ---Gene Therapy for Liver Tumours -- Adenovirus-mediated Transfer of a p53 Gene in Ovarian Cancer -- Other Systems -- Eliciting Hyperacute Rejection as a Tumor Killing Strategy -- Innate Immune Therapy For Cancer -- Mda-7, A Novel Melanoma Differentiation Associated Gene with Promise for Cancer Gene Therapy -- Antisense and Ribozymes -- Antisense IGF and Antisense IGF-IR Therapy of Malignancy -- Sensitization of Tumors to Chemotherapy Through Gene Therapy -- Design and Testing of Ribozymes for Cancer Gene Therapy -- Ribozymes -- The Approach of Triple Helix Formation in Control of Gene Expression and The Treatment of Tumors Expressing IGF-I -- Immuno-Modulation -- Dendritic Cell-based Immunization for Cancer Therapy -- Hybrid Cell Vaccination for Cancer Immunotherapy -- Modulation of the Immune Response Through 4-1BB -- Heat Shock Proteins in Cancer Therapy -- Bi-Specific Antibodies in Cancer Therapy -- B7.1 and Cytokines ---Intralesional Vaccinia/GM-CSF Recombinant Virus in the Treatment of Metastatic Melanoma -- Suicidal Genes -- Approaches to Gene-Directed Enzyme Prodrug Therapy (GDEPT) -- Suicide Gene Therapy -- Adenoviruses as Gene Delivery Vectors -- Angiogenesis Control -- Evaluation of an Inhibitor of DNA Methylation, 5-aza-2?-Deoxycytidine, for The Treatment of Lung Cancer and the Future Role of Gene Therapy -- Vascular Endothelial Growth Factor as a Target for Cancer Gene Therapy -- Adeno-Associated Virus and Other Potential Vectors for Angiostatin and Endostatin Gene Therapy -- Matrix Metallo Proteinase -- Potential Applications of Tissue Inhibitor of Metalloproteinase (TIMP) Overexpression For Cancer Gene Therapy.
Elektronická reprodukce.
Keywords: genetická terapie; nádory -- terapie; Genetic Therapy; Neoplasms; e-knihy online; e-books online